In the new era of functional and molecular imaging, both currently available imaging biomarkers and biomarkers under development are expected to lead to major changes in the management of oncological patients. This well-illustrated two-volume book is a practical manual on the various imaging techniques capable of delivering functional information on cancer, including preclinical and clinical imaging techniques, based on US, CT, MRI, PET and hybrid modalities. This first volume explains the biophysical basis for these functional imaging techniques and describes the techniques themselves. Detailed information is provided on the imaging of cancer hallmarks, including angiogenesis, tumor metabolism, and hypoxia. The techniques and their roles are then discussed individually, covering the full range of modalities in clinical use as well as new molecular and functional techniques. The value of a multiparametric approach is also carefully considered.

Musculoskeletal (MSK) radiology is a radiological subspecialty that has expanded its knowledge base and imaging capabilities with the advent of MRI, multi/detector CT, ult- sound, and PET. Prior to the advent of MRI, MSK radiologists used plain flm X-rays and arthrograms as their primary tools. The subspecialty has progressed from primary im- ing of osseous structures and indirect imaging of joint spaces, to direct imaging of soft tissue structures with direct visualization and fne defnition of MSK structures. A specialized MSK radiologist requires a sound knowledge of anatomy, pathophysi- ogy, orthopedic surgical techniques, and advancements in imaging modalities. MSK im- ing involves all aspects about anatomy, function, disease states, and aspects of interventional radiology appertaining to the MSK system including imaging in orthopedics, trauma, rheumatology, metabolic and endocrine diseases, as well as aspects of pediatrics, oncology, and sports imaging. Subspecialty training in MSK radiology must ensure competence to obtain experience in the following techniques: plain radiography, ultrasonography, CT, MRI, nuclear me- cine, bone densitometry, and fuoroscopic procedures including arthrography. MSK ra- ologists must be aware of the strengths and weaknesses of the different imaging methods in each pathological condition and choose the appropriate imaging technique and/or the appropriate sequence in the investigation of specifc clinical problems.

This introduction to genitourinary and pelvic radiology is a further volume in the Learning Imaging series. Written in a case-based format, the book is subdivided into ten chapters: kidney; adrenal gland; urinary bladder, collecting system and urethra; prostate and seminal vesicles; scrotum; obstetrics; uterus; cervix and vagina; adnexa and retroperitoneum. Genitourinary radiology has undergone a tremendous change owing to advances in ultrasound, CT and MRI that have redefined our understanding of genitourinary and pelvic pathology. Each chapter includes an introduction and ten case studies with illustrations and comments from anatomical, physiopathological and radiological standpoints and with bibliographic recommendations.

In the new era of functional and molecular imaging, both currently available imaging biomarkers and biomarkers under development are expected to lead to major changes in the management of oncological patients. This two-volume book is a practical manual on the various imaging techniques capable of delivering functional information on cancer, including diffusion MRI, perfusion CT and MRI, dual-energy CT, spectroscopy, dynamic contrast-enhanced ultrasonography, PET, and hybrid modalities. This second volume considers the applications and benefits of these techniques in a wide range of tumor types, including their role in diagnosis, prediction of treatment outcome, and early evaluation of treatment response. Each chapter addresses a specific malignancy and is written by one or more acclaimed experts. The lucid text is complemented by numerous high-quality illustrations that highlight key features and major teaching points.